python gui programming [closed]

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What is the difference between Python Tkinter , wxWidgets (or is it called wxPython) and PyQT. Which one is better ?

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This really depends on what you're planning to do with them. Are you writing a GUI "hello world", or planning to do something more serious? Is it for commercial or non-commercial use?

Here's a comparison of WxWidgets against other platforms. That can get you started on the major points of difference. If you want a more specific answer, then please ask a more specific question.