Search and replace operation

I have a list which has URL values like:

http://far开发者_Python百科m6.static.flickr.com/5149/5684108566_aed8b9b52d_s.jpg

How can I change the _s in the end to _m for all occurrences?

Try this:

str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.jpg"
str = str.replace("_s","_m")

If you want to be sure that only the las part is changed and you know all are .jpg files you can use:

str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.jpg"
str = str.replace("_s.jpg","_m.jpg")

To give some more context and avoid changes on the middle of the url.

Or if you want to be able to do this on any file extension and make sure nothing in the string is altered except for the last part.

import re

str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.jpg"
re.sub("(.*)_s(\.[a-z0-9]{1,4})$", r"\1_m\2", str)
str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.png"
re.sub("(.*)_s(\.[a-z0-9]{1,4})$", r"\1_m\2", str)
str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.gif"
re.sub("(.*)_s(\.[a-z0-9]{1,4})$", r"\1_m\2", str)
str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.zip"
re.sub("(.*)_s(\.[a-z0-9]{1,4})$", r"\1_m\2", str)

Output:

>>> str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.jpg"
>>> re.sub("(.*)_s(\.[a-z0-9]{1,4})$", r"\1_m\2", str)
'http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_m.jpg'

>>> str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.png"
>>> re.sub("(.*)_s(\.[a-z0-9]{1,4})$", r"\1_m\2", str)
'http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_m.png'

>>> str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.gif"
>>> re.sub("(.*)_s(\.[a-z0-9]{1,4})$", r"\1_m\2", str)
'http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_m.gif'

>>> str = "http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_s.zip"
>>> re.sub("(.*)_s(\.[a-z0-9]{1,4})$", r"\1_m\2", str)
'http://farm6.static.flickr.com/5149/5684108566_aed8b9b52d_m.zip'