Store file mapping from local to cloud

In Python, what do you believe is the best way to store file mapping info from local mac开发者_高级运维hine to cloud storage?

i.e. A user has 10 files in 3 different folders on his local machine. They are also stored on a cloud storage, each identify by URL or other descriptors.

Best way - in terms of scallability, search/insert efficiency, etc.

You can either use the rsync program, or the rsync algorithm implemented in Python. Assumably you can have access to the remote files over something that looks like a file system, like WebDAV.

Best