Split a paragraphs using RegularExpression (Regex).?

How can I split a paragraph using following methods

First Method =  {A-Z} <br>

Second Method =  {A-Z}<br>

Third Method =  {A-Z}.<br>

Fourth Method =  {A-Z}.\r\n

>

Note: Input may contain combination of all above methods.

Please help me to find out correct Regex Formula for splitting below paragraphs.

Input paragraphs:

{A}<br> Circulation Research. 2000;87:540-542
<br><br>
For a more detailed discussion of the mechanisms underlying the relationship between nitric oxide and telomerase activation, see this study:<br>
Farsetti.  <aomerase tale in vascular aging Journal of Applied Physiology January 2009 vol. 106 no. 1 333-337
<br><br>
{B} <br>
Chauhan. =&_orig=search&_sort=d&view=c&_version=1&_urlVersion=0&_userid=10&md5=c130cff602472f25bd5680ea3047490c" target="_blank">"Aging-Associated Endothelial Dysfunction in Humans Is Re开发者_高级运维versed by L-Arginine"</a> Journal of the American College of Cardiology Volume 28, Issue 7, December 1996, Pages 1796-1804
<br><br>
{C}.<br>
Monajemi H target="_blank">Gene Expression in Atherogenesis"</a>.  <i>Thromb Haemost</i>. 2001 Jul;86(1):404-12.
<br>
{D}.
Britten M. The role of endothelial function of ischemic manifestations of coronary atherosclerosis
<br>
Kimura Y. Impaired endothelial function in hypertensive elderly patients evaluated by high..
<br><br>
{E}.<br>
9. In Cells, Aging and Human Disease, page 170, Michael Fossel writes:
<br>
In comparing young normal human aortic endothelial cells to senescent endothelial cells and endothelial cells imoortalized with hTERT, we find differences. Compared to young endothelial cells, senescent endothelial cells show a decreased production and activity of NO, changes critial in atherogenesis and hypertension. Similarly, senescent endothelial cells demonstrate increased monocyte adhesion, again implicated in atherogenesis. [..] In all cases, these differences are amerliorated or normalized by hTERT immortalization.
<br><br>
{F}.<br>
Chang E, Harley CB. Telomere length and replicative aging in human vascular tissues.

It's hard to tell from your example because the formatting is a bit off. It seems like the cases to cover are:

• optional whitespace (line breaks etc.)
• {
• a letter A-Z
• }
• an optional dot
• whitespace (line breaks etc.)

If that's true, then splitting the input by

\s*\{[A-Z]\}\.?\s*

should work.

In C#:

splitArray = Regex.Split(subjectString, @"\s*\{[A-Z]\}\.?\s*");