What's the best deployment strategy for ASP.NET

I work for an ISV and we have a vanilla ASP.NET (no mvc) web application which we deploy to our customer sites.

We're currently doing开发者_开发技巧 it via xcopy and IIS manually.

What's the best technology to use to deploy it? ClickOnce? WebDeploy? Something else?

Tips appreciated.

WebDeploy FTW.

Check out this excellent article/video from Scott Hanselman.

Handles config transformations as well as the painful task of database deployments.

I just implemented Web Deploy this afternoon by following this article by Scott Gu and I've found it extremely useful.