Strange sharepoint error at UserProfile Application

this is a new sharepoint inst开发者_Python百科allation, and I have this problem when I navigate to the newly installed site.

Any help please

Check permissions of application pool account and UPA account. Note that UPA permissions may be configured in two places in Central Admin: one under "administrators" and other under "permissions" while configuring UPA.

Also you should check timeout values in web.config located in same directory as UPA wcf service. Use IIS Manager to find it and try to increase timeout. I have had similar issue while SharePoint was hosted on slow machine.

Your User Profile service application is corrupt. Delete and recreate UPSA.