deploy application dependencies to program folder or GAC [duplicate]

This question already has answers here: Closed 11 years ago.

Possible Duplicate:

When should I deploy my assemblies into the GAC?

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How do you deploy your applications?

• copy all necessary DLLs (your own, 3rd party, etc.) into the application folder and be finished

or

• deploy some or all dependent DLLs to the GAC

Is there a best practice which of the above solutions to use and which DLLs go into the application folder vs GAC?

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I am using ClickOnce. So, I do not worry about versioning, GAC and other stuff, i just create additional folders in project solutions to copy 3-d party assemblies into, and do not have any of difficulties with updates, besause it is very easy to implement custom update system using built-in update system and reflection (for custom versioning), you can easily find this information about ClickIOnce deployment and custom updates

for simplicity, i recommend to use this directory structure:

<assembly set>\<assembly name>\<assembly version>\

For example:

media\ui\1.0.0.0\ui.dll

or

assemblies\libvnc\1.11.10\libvnc.dll