In debug mode, the execution doesn't always stop on my breakpoints

I've got a weird problem in Visual Studio when I execute some C# code in debug mode. I set some breakpoints and I execute my code step by step but sometimes, when I press F10, the execution continues as if I pressed F5 but won'开发者_运维知识库t stop on my breakpoints anymore until I compile the solution again.

When I clean the solution and restart my computer, it could fix the problem but it'll eventually reoccur.

Did you ever have this problem and what is the solution?