VS2008 - Memory issue when generating manifest

Having made changes and going into debug mode in Visual studio 2008, I often get messages such as:

"Problem generating manifest. Insufficient memory to continue the execution of the program. \WINDOWS\Microsoft.NET\Framework\v3.5\Microsoft.Common.targets 2341 9 ZEUS(my project name)"

By closing and reopening VS the problem temorarily goes away - as though some temp core is being freed up. My PC has lots of memory available - but VS seems lim开发者_运维问答ited to what it can use (????) or is there a way to allocate more. As my project is growing, the problem is becoming more and more frequent.

Anyone else suffering from this ?? Any ideas on how to resolve ??